UvA

Many rheological properties of blood, along with transport properties of blood cells can be captured by means of modeling blood through its main constituents, red blood cells (RBCs) and plasma. In the current work, we present a fully resolved two-dimensional model for blood suspension flow, employing a discrete element model (DEM) for RBCs and coupling it to a lattice Boltzmann method (LBM) fluid solver using the immersed boundary method (IBM). We identify an efficient computationally reduced mesoscopic representation of cells and flow, still able to recover essential physics and physiological phenomena. Our model is found to agree quantitatively with experimental findings. The Fåhræus-Lindqvist effect and shear thinning is recovered, while the thickness of the cell-free layer (CFL) matches the observations. In addition, we investigate the tank-treading frequency of a single RBC in shear flow along with the transition from tumbling to tank-treading, also matching experimental data.