- Experimental strategies directed at inflammation and coagulation in ARDS and TRALI
- Award date
- 19 September 2013
- Number of pages
- Document type
- PhD thesis
- Faculty of Medicine (AMC-UvA)
In this thesis, the effect of blood transfusion on pulmonary inflammation and coagulation was studied. We investigated the role of different mediators in acute respiratory distress syndrome (ARDS) or transfusion-related acute lung injury (TRALI). Furthermore, we tested several therapeutic strategies in murine models of both ARDS and TRALI. The effect of aspirin on TRALI incidence was tested. Lastly, we performed a systematic review on nebulized anticoagulants in the setting of lung injury in animals and humans.
- Research conducted at: Universiteit van Amsterdam
If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library, or send a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.