- Role of Tbx3 in conduction system development
- Award date
- 19 December 2012
- Number of pages
- Document type
- PhD thesis
- Faculty of Medicine (AMC-UvA)
This thesis explores the role of transcription factor Tbx3 in the developing and mature cardiac conduction system. In the adult heart, the conduction system is responsible for the initiation and coordination of the rhythmic contraction of the heart. By studying Tbx3, we have gained further insight into the mechanisms of heart development in general and conduction system development and function in particular. These insights will provide clues for how to stratify arrhythmia risk, predict drug response and develop strategies for new therapies.
- Research conducted at: Universiteit van Amsterdam
If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library, or send a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.