- Author
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H.G. Ruhé
- Title
- Dose-escalation in the picture : pharmacological and imaging studies in depression
- Supervisors
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A.H. Schene
- Co-supervisors
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J. Booij
- Award date
- 5 November 2008
- Number of pages
- 300
- ISBN
- 9789090235592
- Document type
- PhD thesis
- Faculty
- Faculty of Medicine (AMC-UvA)
- Note
- Research conducted at: Universiteit van Amsterdam
- Permalink
- http://hdl.handle.net/11245/1.385714
- Downloads
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Thesis
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Cover
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Title pages
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Contents
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Chapter 1: General introduction and outline of the thesis
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Chapter 2: Design and methods of the DELPHI-study
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Chapter 3: Clinical use of the Hamilton Depression Rating Scale : is increased efficiency possible? A post hoc comparison of HDRS, Maier and Bech subscales, CGI and SCL-90 scores
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Chapter 4: Dose-escalation for insufficient response to a standard dose of a selective serotonin reuptake inhibitor in major depressive disorder : a systematic review
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Chapter 5: Switching antidepressants after a first selective serotonin reuptake inhibitor in major depressive disorder : a systematic review
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Chapter 6: Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans : a meta-analysis of monoamine depletion studies
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Chapter 7: Serotonin transporter binding with [123I]ß-CIT SPECT in major depressive disorder versus controls : effect of season and gender
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Chapter 8: Serotonin transporter gene promoter polymorphisms modify the association between paroxetine serotonin transporter occupancy and clinical response in major depressive disorder
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Chapter 9: Evidence why paroxetine dose-escalation is not effective in major depressive disorder : a randomized-controlled trial with assessment of serotonin transporter occupancy
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Chapter 10: Successful pharmacological treatment of major depressive disorder attenuates amygdala activation to negative facial expressions : an fMRI study
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Chapter 11: Effect of the selective serotonin reuptake inhibitor paroxetine on platelet function is modified by a SLC6A4 serotonin transporter polymorphism
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Chapter 12: Summary, conclusions and general discussion
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Chapter 13: Samenvatting en conclusies
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Abbreviations
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Color figures
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Publications
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Dankwoord
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Curriculum vitae
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