Well-being and co-morbidity in recent onset schizophrenia

van Nimwegen, L.J.M.

Author: L.J.M. van Nimwegen
Title: Well-being and co-morbidity in recent onset schizophrenia
Supervisors: D.H. Linszen
M.W. Hengeveld
Co-supervisors: L. de Haan
W. van den Brink
Award date: 15 October 2008
Number of pages: 167
ISBN: 9789085594178
Document type: PhD thesis
Faculty: Faculty of Medicine (AMC-UvA)
Note: Research conducted at: Universiteit van Amsterdam
Permalink: http://hdl.handle.net/11245/1.385607

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Thesis
Cover
Titlepage
Contents
General introduction
Introduction
Structure and aims of the thesis
Part I: Antipsychotic medication, subjective well-being, craving for and use of cannabis and discontinuation of antipsychotics
1.1: Adolescence, schizophrenia and drug abuse: a window of vulnerability
1.2: Effect of olanzapine and risperidone on subjective well-being and craving for cannabis in patients with schizophrenia or related disorders: a double blind randomized trial
1.3: Early withdrawal in a double-blind randomized clinical trial with olanzapine and risperidone performed in adolescents with first psychosis
1.4: Effect of early dysphoric response and cannabis use on discontinuation of olanzapine and risperidone in young adults with recent onset schizophrenia and related disorders
1.5: Improvement of subjective well-being and enduring symptomatic remission, a 5-year follow up of first episode schizophrenia
Part II: Obsessive-compulsive symptoms in recent onset schizophrenia
2.1: Obsessive-compulsive symptoms in a randomized double blind study with olanzapine or risperidone in youg patients with early psychoses
2.2: The catechol-o-methyltransferase gene and obsessive-compulsive symptoms in patients with recent onset schizophrenia
Part III: Insulin resistance in neuroleptic naive patients with recent onset schizophrenia
3.1: Hepatic insulin resistance in antipsychotic naive schizophrenic, schizo-affective patients, a detailed study of glucose metabolism with stable isotopes
General discussion, conclusions and implications
Summary
Samenvatting
Dankbetuiging
Curriculum Vitae

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