- Mechanisms of osteocyte mechanotransduction
- Clinical Reviews in Bone and Mineral Metabolism
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- Document type
- Faculty of Dentistry (ACTA)
- Healthy bones combine a proper resistance against fracture with a minimum use of material. This property is likely brought
about by osteocytes in response to mechanical cues, but it is still unknown how whole bone loads are translated into a signal
that can be sensed by the osteocytes. The goal of this chapter is to critically analyze our current knowledge on how bone
transduction takes place from the level of mechanical loads placed upon the bone as an organ to activation of a cell.
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