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Author
G.J.W. van der Windt
Title
The role of CD44 and osteopontin in infection and inflammation
Supervisors
T. van der Poll
Co-supervisors
A.F. de Vos
Award date
1 April 2010
Number of pages
224
ISBN
9789090251981
Document type
PhD thesis
Faculty
Faculty of Medicine (AMC-UvA)
Permalink
http://hdl.handle.net/11245/1.342327
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  • Thesis

  • Cover

  • Title pages

  • Table of contents

  • Chapter 1: General introduction and outline of the thesis

  • Chapter 2: CD44 is protective during hyperoxia induced lung injury

  • Chapter 3: CD44 deficiency is associated with enhanced Escherichia coli induced proinflammatory cytokine and chemokine release by peritoneal macrophages

  • Chapter 4: The role of CD44 in the acute and resolution phase of the host response during pneumococcal pneumonia

  • Chapter 5: CD44 facilitates bacterial growth yet limits lung inflammation during gram-negative pneumonia

  • Chapter 6: IRAK-M impairs host defense during bacterial pneumonia

  • Chapter 7: Osteopontin promotes host defense during Klebsiella pneumoniae induced pneumonia

  • Chapter 8: Osteopontin impairs host defense during pneumococcal pneumonia

  • Chapter 9: Osteopontin impairs host defense during established gram-negative sepsis (melioidosis)

  • Chapter 10: Osteopontin is not crucial to protective immunity during murine tuberculosis

  • Chapter 11: Summary and general discussion

  • Nederlandse samenvatting

  • Dankwoord

  • List of publications

  • Curriculum vitae

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