The role of CD44 and osteopontin in infection and inflammation

van der Windt, G.J.W.

Author: G.J.W. van der Windt
Title: The role of CD44 and osteopontin in infection and inflammation
Supervisors: T. van der Poll
Co-supervisors: A.F. de Vos
Award date: 1 April 2010
Number of pages: 224
ISBN: 9789090251981
Document type: PhD thesis
Faculty: Faculty of Medicine (AMC-UvA)
Permalink: http://hdl.handle.net/11245/1.342327

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Thesis
Cover
Title pages
Table of contents
Chapter 1: General introduction and outline of the thesis
Chapter 2: CD44 is protective during hyperoxia induced lung injury
Chapter 3: CD44 deficiency is associated with enhanced Escherichia coli induced proinflammatory cytokine and chemokine release by peritoneal macrophages
Chapter 4: The role of CD44 in the acute and resolution phase of the host response during pneumococcal pneumonia
Chapter 5: CD44 facilitates bacterial growth yet limits lung inflammation during gram-negative pneumonia
Chapter 6: IRAK-M impairs host defense during bacterial pneumonia
Chapter 7: Osteopontin promotes host defense during Klebsiella pneumoniae induced pneumonia
Chapter 8: Osteopontin impairs host defense during pneumococcal pneumonia
Chapter 9: Osteopontin impairs host defense during established gram-negative sepsis (melioidosis)
Chapter 10: Osteopontin is not crucial to protective immunity during murine tuberculosis
Chapter 11: Summary and general discussion
Nederlandse samenvatting
Dankwoord
List of publications
Curriculum vitae

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