- Author
- Year
- 2009
- Title
- Gracilioethers A-C, Antimalarial Metabolites from the Marine Sponge Agelas gracilis
- Journal
- Journal of Organic Chemistry
- Volume | Issue number
- 74 | 11
- Pages (from-to)
- 4203-4207
- Document type
- Article
- Faculty
- Faculty of Science (FNWI)
- Abstract
- Three new antiprotozoan compounds, gracilioethers A−C (1−3), have been isolated from the marine sponge Agelas gracilis. Their structures were elucidated on the basis of spectroscopic and chemical methods. Gracilioethers A−C showed antimalarial activity against Plasmodium falciparum with IC50 values of 0.5−10 μg/mL, whereas gracilioether B (2) also showed antileishmanial activity.
- URL
- go to publisher's site
- Language
- English
- Permalink
- http://hdl.handle.net/11245/1.333961
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