The increasing time spent indoors combined with the abundant usage of diverse indoor chemicals led to concerns involving the
impact of these compounds on human health. The current study focused on two groups of important indoor contaminants i.e. Brominated
flame retardants (BFRs) and Perfluorinated compounds (PFCs). Concentrations of both compound classes have been measured in
Flemish indoor dust samples from homes and offices. Sigma Polybrominated diphenyl ethers (PBDEs) (BDE 47, 99, 100, 154, 153,
197, 196 and 203) and BDE 209 in homes ranged between 4-1214 ng g(-1) dw (median 35) and <5-5295 ng g(-1) dw (median 313).
respectively. Hexabromocyclododecane (Sigma HBCD) levels ranged from 5 to 42 692 ng g(-1) dw (median 130), with alpha-HBCD
being the major isomer (mean 59%). In addition, tetrabromobisphenol A (TBBPA) ranged between <3 and 419 ng g(-1) dw (median
12). For all BFRs, median levels in office dust were up to an order of magnitude higher than in home dust. Sigma PFCs (sum
of perfluorobutane sulfonate (PFBS), perfluorohexane sulfonate (PFHxS), perfluorooctane sulfonic acid (PFOS), perfluorobutanoic
acid (PFBA), perfluorohexanoic acid (PFHxA), perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA) and perfluorodecanoic
acid (PFDA)) concentrations in homes ranged from 0.2 to 336 ng g(-1) (median 3.0 ng g(-1)). Levels in office dust were higher
(p < 0.01) than in house dust with Sigma PFCs ranging between 2.2 and 647 ng g(-1) (median 10 ng g(-1)) and median (PFOA)
and perfluorooctane sulfonate values of 2.9 and 2.2 ng g(-1), respectively. The congener pattern was dominated by PFOA, followed
by PFOS. Calculated human exposure was below the reference dose values set by the US-EPA for BDE 209, HBCD and below the provisional
tolerable daily intakes proposed by European Food Safety Authority for PFOS and PFOA.