M.B. van Veenendaal
F.H.C. de Jongh
J.H. van der Lee
A.H. van Kaam
- Effect of closed endotracheal suction in high-frequency ventilated premature infants measured with electrical impedance tomography
- Intensive Care Medicine
- Volume | Issue number
- 35 | 12
- Pages (from-to)
- Document type
- Faculty of Medicine (AMC-UvA)
Objective: To determine the global and regional changes in lung volume during and after closed endotracheal tube (ETT) suction in high-frequency ventilated preterm infants with respiratory distress syndrome (RDS).
Design: Prospective observational clinical study.
Setting: Neonatal intensive care unit.
Patients: Eleven non-muscle relaxed preterm infants with RDS ventilated with open lung high-frequency ventilation (HFV).
Interventions: Closed ETT suction.
Measurements and results: Changes in global and regional lung volume were measured with electrical impedance tomography. ETT suction resulted in an acute loss of lung volume followed by spontaneous recovery with a median residual loss of 3.3% of the maximum volume loss. The median stabilization time was 8 s. At the regional level, the lung volume changes during and after ETT suction were heterogeneous in nature.
Conclusions: Closed ETT suction causes an acute, transient and heterogeneous loss of lung volume in premature infants with RDS treated with open lung HFV.
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