R.W.M. van Soest
- Dibromotyrosine derivatives, a maleimide, aplysamine-2 and other constituents of the marine sponge Pseudoceratina purpurea.
- Zeitschrift für Naturforschung. B, A Journal of Chemical Sciences
- Volume | Issue number
- 60 | 8
- Pages (from-to)
- Number of pages
- Document type
- Faculty of Science (FNWI)
- A collection of the marine sponge Pseudoceratina purpurea from the Gulf of Thailand furnished aplysamine-2, two new bromotyrosine derivatives purpuroceratic acids A and B, two known bromotyrosine derivatives, 3-maleimide-5-oxime and common sponge constituents. Aplysamine-2, purpuroceratic acid A and 3-maleimide oxime were evaluated for their in vitro anticancer activity against three cancer cell lines, but only aplysamine-2 exhibited moderate dose dependent growth inhibitory effects.
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