UvA- Author
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J.W. Jonker
- Title
- Pharmacological and physiological functions of polyspecific drug transporters
- Supervisors
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P. Borst
- Co-supervisors
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A.H. Schinkel
- Award date
- 12 September 2003
- Number of pages
- 123
- ISBN
- 9064646899
9789064646898 - Document type
- PhD thesis
- Faculty
- Faculty of Medicine (AMC-UvA)
- Note
- Research conducted at: GEMO
- Permalink
- http://hdl.handle.net/11245/1.212504
- Downloads
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Thesis
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Cover
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Titlepage
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Contents
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Chapter 1 Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
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Chapter 2 Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug
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Chapter 3 Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan
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Chapter 4 The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
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Chapter 5 Pharmacological and physiological functions of the polyspecific organic cation transporters OCT1, 2 and 3 (SLC22A1-3)
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Chapter 6 Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) gene
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Chapter 7 Deficiency in the Organic Cation Transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations
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Summary & Samenvatting
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Dankwoord
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Curriculum vitae
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List of publications
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Abbreviations
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Cover
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