UvA- Author
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V. de Haas
- Title
- Quantitative analysis of minimal residual disease by PCR in childhood acute lymphoid leukemia
- Supervisors
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P.A. Voûte
A.E.G.Kr. von dem Borne - Co-supervisors
- Award date
- 15 June 2001
- Number of pages
- 133
- Publisher
- 2001: in eigen beheer
- ISBN
- 9090147551
9789090147550 - Document type
- PhD thesis
- Faculty
- Faculty of Medicine (AMC-UvA)
- Note
- Research conducted at: Geneeskunde
- Permalink
- http://hdl.handle.net/11245/1.181265
- Downloads
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Thesis
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Cover
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Titlepage
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LIST OF ABBREVIATIONS
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TABLE OF CONTENTS
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Chapter 1 GENERAL INTRODUCTION
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Chapter 2 QUANTIFICATION OF MINIMAL RESIDUAL DISEASE IN CHILDREN WITH OLIGOCLONAL B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA INDICATES THAT THE CLONES THAT GROW OUT DURING RELAPSE HAVE THE SLOWEST RATE OF REDUCTION ALREADY DURING INDUCTION THERAPY
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Chapter 3 MRD STUDIES ARE BENEFICIAL IN THE FOLLOW-UP OF TEL-AML1 PATIENTS WITH B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA
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Chapter 4 THE TEL-AML1 RQ-PCR CAN REPLACE THE ANTIGEN-RECEPTOR BASED GENOMIC PCR IN CLINICAL MRD STUDIES IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
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Chapter 5 ACCURATE QUANTIFICATION OF MINIMAL RESIDUAL DISEASE AT DAY 15, BY REAL-TIME QUANTITATIVE POLYMERASE CHAIN REACTION, IDENTIFIES ALSO PATIENTS WITH B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA AT HIGH RISK FOR RELAPSE
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Chapter 6 NO CLEAR RELATION BETWEEN IN VITRO DRUG RESISTANCE AND LEVEL OF MINIMAL RESIDUAL DISEASE (MRD) AS DETECTED BY PCR AT THE END OF INDUCTION THERAPY IN CHILDHOOD ALL
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Chapter 7 EARLY DETECTION OF CENTRAL NERVOUS SYSTEM RELAPSE BY PCR IN CHILDREN WITH B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA
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Chapter 8 SUMMARY, GENERAL DISCUSSION AND FUTURE PERSPECTIVES
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Chapter 9 NEDERLANDSE SAMENVATTING
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REFERENCES
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DANKWOORD PUBLICATIONS CURRICULUM VITAE
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PUBLICATIONS
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CURRICULUM VITAE
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Cover
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