University of AmsterdamUniversity of AmsterdamUvA

  • Terms of use
  • Contact

UvA-DARE (Digital Academic Repository)

  • Home
  • Advanced Search
  • Browse
  • My selection

Search UvA-DARE

Author
M. Smits
A. van Maanen
A.M. Meijer
K. van der Heijden
F. Oort
Date
12-2017
Title
Cognitive, health and psychosocial effects of melatonin and light therapy in childhood insomnia. Double-blind placebo-controlled study
Journal
Sleep Medicine
Volume | Issue number
40 | Supplement 1
Article number
e310
Number of pages
1
Document type
Meeting Abstract
Faculty
Faculty of Social and Behavioural Sciences (FMG)
Institute
Research Institute of Child Development and Education (RICDE)
Abstract
Introduction: To examine effects of melatonin and light therapy on cognitive, health and psychosocial outcomes in children with chronic sleep onset insomnia; and to disentangle direct effects from indirect effects through sleep improvement.

Methods: A randomized, double-blind placebo-controlled trial was conducted in which 84 children received melatonin treatment, placebo pills, or light therapy for three to four weeks, after a baseline period of one week. Daily sleep measures were obtained through actigraphy, and children completed cognitive tasks (simple reaction time, visuomotor control, working memory and selective attention) and parents and children completed questionnaires concerning health, mood, school functioning, behavioral and attention problems, at baseline and post-treatment. Regression analyses with bootstrapping were carried out to disentangle direct and indirect (i.e. through sleep) effects.

Results: Melatonin treatment improved health and light therapy decreased behavior problems. Although both treatments improved sleep, the treatment effects on health and behavior problems were not mediated by sleep.

Conclusions: Melatonin and light therapy improved chronic sleep onset problems in children, but fewer effects were found on cognitive, health and psychosocial functioning, and these effects were not mediated by sleep improvement.

Acknowledgements: Pharma Nord sponsored the melatonin and placebo tablets for the study, Physician Engineered Products offered the light devices with discount. Both companies were not involved in the study and report of the results.
URL
go to publisher's site
Language
English
Note
In: World Association of Sleep Medicine abstracts
Permalink
http://hdl.handle.net/11245.1/f43f9223-61d3-4142-abe4-df4001e153a7

Disclaimer/Complaints regulations

If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library, or send a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.

PrintPrint this pageShareShare via emailShare on facebookShare on linkedinShare on twitter
  • University library
  • About UvA-DARE
  • Disclaimer
Copyright UvA 2014