- Person-environmental interactions in psychosis
L. de Haan
- Award date
- 20 March 2018
- Number of pages
- Document type
- PhD thesis
- Faculty of Medicine (AMC-UvA)
This thesis’ first aim was to evaluate various potential pathways to development- and course of psychotic symptoms and disorders. The data used concerned part of the Dutch national Genetic Risk and Outcome of Psychosis (GROUP) study. In particular research questions addressed processes related to the ‘vulnerability-stress model’. This thesis found further support for interactions between certain environmental risk factors and vulnerability factors for psychosis. Vulnerability factors studied included familial risk for psychosis, impaired social cognition, insecure attachment styles, certain personality traits and subjective well-being. Environmental risk factors studied were childhood trauma and adult life events. Its second aim was to evaluate effectiveness of cognitive behavioural approaches to psychosis. The effectiveness of metacognitive therapy was compared with occupational therapy in people with a recent-onset psychotic disorder. Findings suggest favorable effects of metacognitive training on paranoid reactivity compared to occupational therapy. Also, a CBT approach focusing on social activation (CBTsa) showed promising results in decreasing social withdrawal in early psychosis patients compared to TAU.
Thesis (complete) (Embargo up to and including 20 March 2020)
Chapter 4: An experience sampling study on the ecological validity of the SWN-20: Indication that subjective well-being is associated with momentary affective states above and beyond psychosis susceptibility (Embargo up to and including 20 March 2019)
Chapter 5: Exploring pathways to paranoid ideation: Is the association between experiencing recent negative life events and paranoia mediated by stress-sensitivity and moderated by level of familial risk for psychosis in support of the vulnerability-stress hypothesis? (Embargo up to and including 20 March 2020)
Chapter 6: Metacognitive Training in patients recovering from a first psychosis: An experience sampling study testing treatment effects (Embargo up to and including 20 March 2019)
Chapter 7: Brief Cognitive Behavioural Therapy for social activation in recent-onset psychosis: A randomized controlled trial (Embargo up to and including 20 March 2020)
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