J.R. Ferreira de Abreu
- Small GTPases : emerging targets in rheumatoid arthritis
- Award date
- 11 December 2009
- Number of pages
- Document type
- PhD thesis
- Faculty of Medicine (AMC-UvA)
- The studies provided in this thesis show that modulation of small GTPase function regulates cellular activation and inflammation in RA and animal models of the disease. Small GTPases are therefore emerging targets in RA and further studies should explore the development of novel small GTPase modulators and evaluate their potential in the treatment of patients with RA.
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