From progenitor cell to immune cell : cytokines and transcription factors in human hematopoietic development

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Author	W. Dontje
Title	From progenitor cell to immune cell : cytokines and transcription factors in human hematopoietic development
Promotor	H. Spits
Co-promotor	B. Blom
Date	03-10-2008
Year	2008
Pages	188
Faculty	AMC-UvA
Keywords	Immune reactions ; Lymphocytes ; Natural killer cells ; Stem cells
Classification	44.45 immunology (medicine)
Language	English
Document type	Dissertation
Download papers	Thesis Cover Title page Contents Chapter 1: Introduction Chapter 2: Role of IL-7 on human lymphoid development and homeostasis in Chapter 3: Delta-like1- induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T cell lineage decision through control of GATA-3 and Spi-B Chapter 4: Stimulated plasmacytoid dendritic cells impair human T cell development Chapter 5: Synergy between IL-15 and Id2 promotes thymic progenitor cells to develop into NK cells Chapter 6: Notch4 and IL-7 signaling cooperate in the development of human IL-7Rα+CD56+ NK cells Chapter 7: FLT3-ITD mutations impair plasmacytoid dendritic cell development through aberrant STAT5 signaling Chapter 8: Discussion Summary Nederlandse samenvatting Dankwoord List of publications
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