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Record: oai:ARNO:122980

AuthorsA. Trouwborst, H. Yanagida, W. Erdmann, A. Kok
TitleMechanism of neuroadenolysis of the pituitary for cancer pain control
JournalApplied-Neurophysiology
Volume47
Year1984
Issue3
Pages97-110
ISSN0379-2676
FacultyFaculty of Social and Behavioural Sciences
AMC-UvA
Institute/dept.FMG: Psychology Research Institute
KeywordsElectroencephalography; Evoked-Potentials; Neural-Pathways; Pain-Perception; Pituitary-Gland
AbstractStudied whether neuronal activity of the pituitary gland, as related to the primary somatosensory cortex, may be involved in the pain perception pathway influenced by neuroadenolysis of the pituitary. EEG and tooth-pulp EPs (TPEPs) were examined in 3 rhesus monkeys (Macaca mulatta). Findings indicate that an increase of TPEPs (hyperactivity) in the pituitary gland was produced after alcohol injection into the sella turcica, leading to a decrease of pain response in the sensory cortex (decrease of TPEPs). This wound effect may have been influenced by endorphins, because naloxone injection reversed the changes in TPEPs in both places
Document typeArticle
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