Shaping the brain through experience: effects of stressful life events on hippocampal neurogenesis, morphology and function

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Author	C.A. Oomen
Title	Shaping the brain through experience: effects of stressful life events on hippocampal neurogenesis, morphology and function
Promotor	M. Joëls
Co-promotors	P. Lucassen, H. Krugers
Date	04-06-2010
Year	2010
Pages	204
Faculty	Faculty of Science
Institute/dept.	FNWI: Swammerdam Institute for Life Sciences (SILS)
Language	English
Note	Published version of chapter 4 available at http://dx.doi.org/10.1523/JNEUROSCI.0247-10.2010
Document type	Dissertation
Download papers	Thesis Front cover Title pages Contents Preface Chapter 1: General introduction Chapter 2: Opposite effects of early maternal deprivation on neurogenesis in male versus female rats Chapter 3: Early maternal deprivation affects dentate gyrus structure and emotional learning in adult females Chapter 4: Severe early life stress hampers spatial learning and neurogenesis, but improves hippocampal synaptic plasticity and emotional learning under high stress conditions in adulthood Chapter 5: Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress Chapter 6: General discussion Addendum: Spatial learning in the Morris water maze reduces newborn cell survival in the rostral hippocampus but does not affect neurogenesis: a discussion of the current state of confusion List of abbreviations Nederlandse samenvatting Dankwoord Curriculum vitae List of publications
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