faculty: "FdG" and publication year: "2007"
| Author||S.L. Knijnenburg|
|Title||Late nephrotoxicity in childhood cancer survivors.|
|Supervisors||L.C. Kremer, M.W.M. Jaspers|
|Faculty||Faculty of Medicine (AMC-UvA)|
|Institute/dept.||FdG: Medische Informatiekunde (MIK)|
|Keywords||Kanker; Kind; Nierziekten; Radiotherapie; Kwaliteit van leven|
|Abstract||In The Netherlands, about 950 children develop cancer each year. Great improvements in treatment for malignant disease in childhood have led to a major increase in survival, reaching up to 85%. As survival has greatly improved, the need to assess the quality of survival has increased correspondingly. Late toxicities of treatment regimes may impair the normal development and maturation in children, cause lifelong ill health or disability or even lead to premature death. To gain more insight in this new area of care, the EKZ/AMC Amsterdam launched an outpatient clinic for five-year survivors of childhood cancer.|
One of the possible late effects is the occurrence of nephrotoxicity. Ifosfamide, platinum derivates, radiotherapy in the kidney region and nephrectomy are known for their late deteriorating effects on the kidneys. In this thesis we describe two studies regarding the prevalence of nephrotoxicity in childhood cancer survivors and the prognostic factors influencing the development of this nephrotoxicity.
|Document type|| scriptie |
Use this url to link to this page: http://dare.uva.nl/en/scriptie/256099
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