faculty: "FNWI" and publication year: "2011"
| Author||Anne Maren Krüse|
|Title||The Effect of Vitamin B12 on Neurocognitive Ageing|
|Supervisors||W.P.M. van den Wildenberg, K.R. Ridderinkhof|
|Faculty||Faculty of Science|
|Programme||FNWI MSc Brain and Cognitive Sciences|
|Keywords||ageing; cognitive decline; vitamin B12; (holotrans)cobalamin; longitudinal; deficiency|
|Abstract||Age-related decline in various cognitive functions is well documented. With a graying world’s population at hand it becomes more and more pressing to examine ways to reduce this cognitive decline and its consequences. Many studies have examined the relationship of vitamin B12 and cognitive performance, but the majority of these studies have been cross-sectional and the results have been largely inconsistent. This literature thesis summarizes and evaluates longitudinal studies that have examined the effect of vitamin B12 deficiency and supplementation on neurocognitive ageing in healthy elderly. A large number of studies find no association between vitamin B12 deficiency and cognitive performance. Supplemental vitamin B12 generally does not improve cognitive performance. However, vitamin B12 status is often measured with insensitive and|
unspecific markers due to a lack of consensus about criteria. Therefore, the results from these studies are not as valid as they appear and the effect of vitamin B12 on neurocognitive ageing
remains unclear. Future research with valid markers is necessary to clarify the effect of vitamin B12 on neurocognitive ageing.
|Document type|| scriptie master|
Use this url to link to this page: http://dare.uva.nl/en/scriptie/408544
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