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Query: faculty: "FNWI" and publication year: "2011"

AuthorS.E. Heethuis
TitleAssessment of pulse wave velocity in coronary arteries
SupervisorsM.C. Rolandi, M. Siebes, E. van Bavel
Year2011
Pages31
FacultyFaculty of Science
AbstractThe wave speed in the coronary arteries is an important value for wave intensity analysis. This is a time-domain method which analysis the pressure and flow velocity at the same time. It is especially well suited for studying coronary hemodynamic signals because it can separate between events coming from the microcirculation and from the aorta (backward and forward waves). Although, to separate the forward and the backward contribution, the wave speed is required. The assessment of the wave speed in coronary arteries is therefore important. For the assessment of wave speed in the aorta several methods are known to be valid, however, this is not the case for the coronary arteries. The goal of this study is to compare several methods: the single-point technique (SPc), an adjusted (high frequency) single-point technique, the PU-loop and the foot-to-foot method (the foot being assessed in three different ways). Several methods are tested in both human measurements and in a laboratory set-up. From the results it can be concluded that the high frequency single-point technique is a better method for assessment of the wave speed in coronary arteries than the normal SPc, although, it seems that it still does not represent the ‘true’ value. In the laboratory set-up is was found that the tangent foot-to-foot method looks promising for the assessment of the wave speed in coronary arteries.
Document type scriptie bachelor
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