KLF2, a critical modulator in vascular disease

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Query: faculty: "AMC-UvA" and publication year: "2009"

Author	J.V. van Thienen
Title	KLF2, a critical modulator in vascular disease
Promotors	H. Pannekoek, A.J.G. Horrevoets
Date	27-01-2009
Year	2009
Pages	185
ISBN	978-90-9023833-3
Faculty	AMC-UvA
Classification	-
Language	English
Document type	Dissertation
Download papers	Thesis Title pages Contents Chapter 1: Introduction Chapter 2: Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes Chapter 3: Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization Chapter 4: Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2 Chapter 5: Endothelial KLF2 regulates mitogen activated protein kinase signaling through RhoA and the actin cytoskeleton Chapter 6: Involvement of KLF2 in endothelial regeneration : a novel target for prevention of in-stent thrombosis and restenosis Chapter 7: Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2 Chapter 8: Incomplete suppression of macrophage inflammatory response by KLF2 aggravates atherosclerosis Chapter 9: General discussion Chapter 10: Summary en samenvatting Dankwoord Publicatielijst Curriculum vitae
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