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Record: oai:ARNO:335049

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AuthorE. Lee
TitleNeural coding of attention and attentional set shifting in the rat medial prefrontal cortex
PromotorC.M.A. Pennartz
Date14-04-2010
Year2010
Pagesiii, 138
ISBN978-90-8570-510-9
FacultyFaculty of Science
Institute/dept.FNWI: Swammerdam Institute for Life Sciences (SILS)
Keywordsattentional set shifting; ensemble recording; multi-electrode recording; multimodal; prefrontal cortex; cognitive control
AbstractWe investigated cognitive control in the rat medial prefrontal cortex (mPFC) and specifically asked how neural activity changes when the animal directs attention to relevant information while ignoring irrelevant inputs. With the multi-tetrode recording technique, we aimed to find out what happens in this brain structure when previously irrelevant information becomes relevant. The new insights we obtained in these mechanisms will aid us in extending our knowledge on the neural basis of neurological disorders involving the frontal lobes including schizophrenia, ADHD and Parkinson's disease.
LanguageEnglish
Document typeDissertation
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