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Record: oai:ARNO:323968

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AuthorJ.R. Ferreira de Abreu
TitleSmall GTPases : emerging targets in rheumatoid arthritis
PromotorP.P. Tak
Co-promotorK.A. Reedquist
Date11-12-2009
Year2009
Pages198
FacultyAMC-UvA
Keywordsrheumatoid arthritis ; small GTPases
AbstractThe studies provided in this thesis show that modulation of small GTPase function regulates cellular activation and inflammation in RA and animal models of the disease. Small GTPases are therefore emerging targets in RA and further studies should explore the development of novel small GTPase modulators and evaluate their potential in the treatment of patients with RA.
LanguageEnglish
Document typeDissertation
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