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Query: journal id: "aids"

AuthorsJ.G.M. Hoefnagel, M.J. Lee, P.P. Koopmans, R. Schuurman, S. Jurriaans, A.I. van Sighem, L. Gras, F. de Wolf, J.M.D. Galama, D.M. Burger
TitleThe genotypic inhibitory quotient and the (cumulative) number of mutations predict the response to lopinavir therapy
JournalAIDS
Volume20
Year2006
Issue7
Pages1069-1071
ISSN02699370
FacultyAMC-UvA
AbstractFor 95 protease inhibitor-experienced HIV-1-infected patients, the genotypic inhibitory quotient (GIQ; trough level/number of mutations) was calculated for lopinavir. Three different sets of mutations showed equal predictive value. However, the use of cumulative numbers of mutations for calculation of the GIQ showed significantly better association with the virological response. Furthermore, the predictive value of the GIQ was no different from that of the number of mutations alone
Document typeArticle
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