Zoekopdracht:
faculteit: "UvA" en publicatiejaar: "2008"
| Auteurs | G. van Andel, A. Bottomley, S.D. Fosså, F. Efficace, C. Coens, S. Guerif, H. Kynaston, P. Gontero, G. Thalmann, A. Akdas, S. D' Haese, N.K. Aaronson | | Titel | An international field study of the EORTC QLQ-PR25: a questionnaire for assessing the health-related quality of life of patients with prostate cancer |
| Tijdschrift | EUR J CANCER |
| Jaargang | 44 |
| Jaar | 2008 |
| Pagina's | 2418-2424 |
| ISSN | 09598049 |
| Faculteit | UvA |
| Samenvatting | Aim: To evaluate the psychometrics of the EORTC QLQ-PR25, a questionnaire assessing the health-related quality of life of prostate cancer patients.
Methods: The QLQ-PR25 and the QLQ-C30 were administered to 642 prostate cancer
patients from 13 countries treated with curative or palliative intent. The QLQ-PR25 assesses urinary, bowel and sexual symptoms and functioning, and the side-effects of hormonal treatment.
Results: Five hundred and nine patients were available for the final analysis. Multitrait scaling analyses confirmed the hypothesised scale structure of the QLQ-PR25. Internal consistency reliability was good (coefficient a = 0.70–0.86) for the urinary symptoms and sexual function scales, but lower for the bowel function and side-effects of hormonal treatment scales (a < 0.70). The module discriminated clearly between clinically distinct patient subgroups, and was responsive to changes in health status over time.
Conclusion: In general, the QLQ-PR25 demonstrates acceptable psychometric properties and clinical validity. Some caution should be used in interpreting the bowel function and sideeffects of hormonal therapy scales; results can be reported at the individual item and scale level. |
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