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Zoekopdracht: faculteit: "ACTA" en publicatiejaar: "2010"

AuteursG. Aarab, F. Lobbezoo, H.L. Hamburger, M. Naeije
TitelEffects of an oral appliance with different mandibular protrusion positions at a constant vertical dimension on obstructive sleep apnea
TijdschriftClinical Oral Investigations
Jaargang14
Jaar2010
Nummer3
Pagina's339-345
ISSN14326981
FaculteitACTA
SamenvattingThe aim of the study was to assess the influence of four mandibular protrusion positions, at a constant vertical dimension, on obstructive sleep apnea (OSA). Seventeen OSA patients (49.2 ± 8.5 years) received an adjustable mandibular advancement device (MAD). The patients underwent four polysomnographic recordings with their MAD in situ at, in random order, 0%, 25%, 50%, and 75% of the maximum protrusion. The mean apnea–hypopnea index (AHI) values of the patients differed significantly between the protrusion positions (P < 0.000). The 25% protrusion position resulted in a significant reduction of the AHI with respect to the 0% position, while in the 50% and 75% positions, even lower AHI values were found. The number of side effects was larger starting at the 50% protrusion position. We therefore recommend coming to a weighted compromise between efficacy and side effects by starting a MAD treatment in the 50% protrusion position.
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