Zoekopdracht:
faculteit: "FNWI" en publicatiejaar: "2011"
| Auteurs | R.J.A.H. Eendebak, P.J. Lucassen, C.P. Fitzsimons | | Titel | Nuclear receptors and microRNAs: who regulates the regulators in neural stem cells? |
| Tijdschrift | FEBS Letters |
| Jaargang | 585 |
| Jaar | 2011 |
| Nummer | 5 |
| Pagina's | 717-22 |
| ISSN | 00145793 |
| Faculteit | Faculteit der Natuurwetenschappen, Wiskunde en Informatica |
| Instituut/afd. | FNWI: Swammerdam Institute for Life Sciences (SILS) |
| Samenvatting | In this mini-review, we focus on regulatory loops between nuclear receptors and microRNAs, an emerging class of small RNA regulators of gene expression. Evidence supporting interactions between microRNAs and nuclear receptors in the regulation of gene expression networks is discussed in relation to its possible role in neural stem cell self renewal and differentiation. Furthermore, we discuss possible disturbances of the regulatory loops between microRNAs and nuclear receptors in human neurodegenerative disease. Finally, we discuss the possible use of nuclear receptors as pharmacological entry points to regulate neural stem cell self-renewal and differentiation. |
| Soort document | Artikel |
| Document finder | 
|
Gebruik dit adres om naar deze pagina te linken: http://dare.uva.nl/record/411414
Vraag/opmerking over dit recordMail aan een collega
Toevoegen aan bewaarset
|
vorige
