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Zoekopdracht: faculteit: "FNWI" en publicatiejaar: "2011"

AuteursJ Sugar, M.P. Witter, N.M. van Strien, N.L.M. Cappaert
TitelThe retrosplenial cortex: intrinsic connectivity and connections with the (para)hippocampal region in the rat. An interactive connectome
TijdschriftFrontiers in Neuroinformatics
FaculteitFaculteit der Natuurwetenschappen, Wiskunde en Informatica
Instituut/afd.FNWI: Institute for Biodiversity and Ecosystem Dynamics (IBED)
FNWI: Swammerdam Institute for Life Sciences (SILS)
SamenvattingA connectome is an indispensable tool for brain researchers, since it quickly provides
comprehensive knowledge of the brain’s anatomical connections. Such knowledge lies at the
basis of understanding network functions. Our first comprehensive and interactive account of
brain connections comprised the rat hippocampal–parahippocampal network. We have now
added all anatomical connections with the retrosplenial cortex (RSC) as well as the intrinsic
connections of this region, because of the interesting functional overlap between these brain
regions. The RSC is involved in a variety of cognitive tasks including memory, navigation, and
prospective thinking, yet the exact role of the RSC and the functional differences between its
subdivisions remain elusive. The connectome presented here may help to define this role by
providing an unprecedented interactive and searchable overview of all connections within and
between the rat RSC, parahippocampal region and hippocampal formation.
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