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Zoekresultaten

Zoekopdracht: faculteit: "ACTA" en publicatiejaar: "2008"

AuteursJ. de Lange, E.M. Baas, R.B.G. Horsthuis, A. Booij
TitelThe effect of nasal application of cocaine/adrenaline on blood loss in Le Fort I osteotomies
TijdschriftInternational Journal of Oral and Maxillofacial Surgery
Jaargang37
Jaar2008
Nummer1
Pagina's21-24
ISSN09015027
FaculteitAMC-UvA
ACTA
SamenvattingCocaine is a very potent vasoconstrictor that is used by ENT specialists to reduce blood loss and enhance visibility during nasal surgery. In orthognathic surgery, especially Le Fort I procedures, excessive blood loss is a relatively frequent complication. In this study, a prospective randomized clinical trial on the effect on blood loss of cocaine/adrenaline application to the nasal floor is presented. Thirty patients who underwent a Le Fort I procedure were randomized for cocaine/adrenaline application. Blood loss and duration of surgery were registered for both groups. The results showed a significant reduction of blood loss in the group with cocaine/adrenaline application (P < 0.001), but no significant difference in operating time. No side effects were observed. From this study, it can be concluded that the application of cocaine/adrenaline to the nasal floor is a safe procedure to reduce blood loss during a Le Fort I procedure.
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